Cryogenic surgery- colon tumor destruction
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Cryogenic surgery- colon tumor destruction

Project period

03/02/2017 - 03/31/2017




Cryogenic surgery- colon tumor destruction
Cryogenic surgery- colon tumor destruction

The colon is another term for the large intestine, it is the lowest part of the digestive system. Inside the colon, water and salt from solid wastes are extracted before the waste moves through the rectum and exits the body through the anus. Along with the development of modern imaging techniques in cancer biology, cryosurgery is emerging as a minimally invasive surgical technique in the treatment of some specific tumors (kidney, breasts, and bones, liver). Here, an alternative approach is proposed for the destruction of colon polyps under cryosurgery with colonoscopy probes. This procedure is relatively safe and the survival rate may be increased, with fewer side effects compared with normal surgical resection and radiotherapies. It completely destructs the colon tumors with a combination of colonoscopy and cryogenic surgery.

Cryosurgery (also called cryotherapy) is the use of extreme cold produced by liquid nitrogen (or argon gas) to destroy abnormal tissue. Cryosurgery is used to treat external tumors, such as those on the skin. For external tumors, liquid nitrogen is applied directly to the cancer cells with a cotton swab spraying device. Cryosurgery is also used to treat tumors inside the body (internal tumors and tumors in the bone). For internal tumors, liquid nitrogen or argon gas is circulated through a hollow instrument called a cryoprobe, which is placed in contact with the tumor. The doctor uses ultrasound or MRI to guide the cryoprobe and monitor the freezing of the cells, thus limiting damage to nearby healthy tissue. (In ultrasound, sound waves are bounced off organs and other tissues to create a picture called a sonogram.) A ball of ice crystals forms around the probe, freezing nearby cells. Sometimes more than one probe is used to deliver the liquid nitrogen to various parts of the tumor. The probes may be put into the tumor during surgery or through the skin (percutaneously). After cryosurgery, the frozen tissue thaws and is either naturally absorbed by the body (for internal tumors), or it dissolves and forms a scab (for external tumors).

Why: Problem statement

Colon cancer is the second largest cancer with a high death rate and it is diagnosed by Colonoscopy test, sigmoidoscopy test, CT/MRI. It is treated by surgery, chemotherapy, radiation, biological therapy. All these above treatments are painful, costly and have more side effects. The colon cancer scenario is given below for reference

How: Solution description

Here a new method of combination of colonoscopy and the cryogenic probe was implemented for improved destructions of colon polyps The theoretical design of combined cryoprobes and colonoscopy probes are shown in the figure below



  • Cryoprobe technology was used to design the cryogenic probe, and the same was analyzed.

  • This was done with the help of a device called cryospray or cryojet with different types of cryoprobes, till ice ball is formed.




  • Colonoscopy probes are thick flexible probes that are used with colonoscopy.
  • The whole colon can be visually inspected, through fiber optic flexible colonoscopy before surgery to rule out multiple polyposes or a synchronous second primary

  • Endoscopic  screening  - ulcers, polyps, tumors, inflammation

  • Flexible tube: 48 in. to 72 in.

How is it different from competition

Since the previous treatments include surgery, chemotherapy, and radiation, biological therapy is painful, invasive and costly. We came up with Cryosurgery which use extreme cold in surgery to destroy abnormal or diseased tissue.

Who are your customers

As cryosurgery is a simple, minimally invasive, cost-effective and easy treatment with minimal pain and scare. It is recommended for all patients irrespective of their ages.

Project Phases and Schedule

Phase 1: Complete the patient section and control section of the abbot.

Phase 2: Complete the robot section and monitor section along with the programming.

Resources Required

  • Cryoprobe
  • Liquid nitrogen or argon gas
  • Ultrasound, 
  • Computed tomography (CT) or magnetic resonance (MR)


    2017-04-02 02:50:35

Great study... Are you implementing it in your project?

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